منابع مشابه
Ocular Drug Delivery
Traditionally, medication is delivered to the eye by three main mechanisms: Topical ocular administration, systemic administration, and intraocular or periocular injection. Each of these methods has significant disadvantages. Topical ocular solutions or ointments have less than a 1% penetration, have rapid dilution and tear washout, and rely substantially on owner compliance to administer the m...
متن کاملOcular drug delivery pdf
Ocular drug delivery research acceleratedly advanced towards. Ocular drug delivery necessitates and helps drug delivery scientists to. Urgent need to develop ocular drug delivery systems which provide controlled. Pdflucentis-prescribing.pdf accessed on 18 October 2010. Delivery system, therefore, desires an integrated knowledge of the drug molecule and the restrictions offered by the ocular rou...
متن کاملDrug Design Concept in Ocular Drug Delivery
Ocular administration of the drug is primarily associated with the need to treat ophthalmic diseases and is not regarded as a means for gaining systemic drug action. Major classes of drugs used are miotics, mydriatics/cyclopegics, anti-inflammatory, antiinfectives, surgical adjutants and diagnostics, which are all meant for local therapy. Systemic action by using eye as a portal is generally av...
متن کاملOcular Drug Delivery Using Microneedles
To my dearest parents For their love, trust and supports ACKNOWLEGMENT I would like to thank my advisor, my thesis committee members, my research colleagues, my family and my friends who made this thesis possible. I would like to thank my thesis advisor, Mark Prausnitz for his support during my thesis work. Without his guidance, it would be difficult for me to complete my study. I would like to...
متن کاملMicroneedles for Ocular Drug Delivery
Statement of Purpose: Targeted drug delivery into the eye is a challenging task because of a variety of barriers that prevent safe and effective delivery. Topical application to the eye is hindered by low residence time resulting in poor diffusion of drug into intraocular tissues. Intravitreal injection can deliver drugs to the retina effectively but is invasive and carries risk of infection. I...
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ژورنال
عنوان ژورنال: NMR in Biomedicine
سال: 2008
ISSN: 0952-3480,1099-1492
DOI: 10.1002/nbm.1230